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Additionally, GLP-1 agonists suppress glucagon secretion from pancreatic alpha cells, slow gastric emptying, and promote satiety through central nervous system effects, contributing to weight loss in many patients

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Announced on Thursday in New York, the Lasker-DeBakey Clinical Medical Research Award will be shared by Svetlana Mojsov and Joel Habener, who identified and characterized the GLP-1 hormone in the 1980s while at Massachusetts General Hospital, and Lotte Knudsen of the Danish pharmaceutical company Novo Nordisk, who led the team that created the first GLP-1-mimicking drug approved for obesity

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